Guidelines 

Evidence-based guidelines for the management of patients with

Head & Neck tumors.

First edition, September 2001

Second edition, September 2003

Third edition, May 2006

 

Editorial board
Vincent GREGOIRE, M.D., PhD. 

Marc HAMOIR, M.D.

Hervé REYCHLER, M.D., D.M.D.


 



 
  

DISCLAIMER

The materials presented in this website illustrates the clinical practice in Head & Neck oncology at the Cliniques Universitaires St-Luc.

Authors are not responsible for any use of these guidelines by third parties.


Table of content


Contributors to the first edition

Foreword to the first edition

Foreword to the second edition

Levels of evidence

Oral cavity carcinoma 

Download high quality PDF file (1083 kb)

Oropharyngeal carcinoma

Download high quality PDF file (952 kb)

Hypopharyngeal carcinoma

Download high quality PDF file (692 kb)

Laryngeal carcinoma

Download high quality PDF file (956 kb)

Nasopharyngeal carcinoma

Download high quality PDF file (560 kb)

Carcinoma of unknown primary

Download high quality PDF file (3734 kb)

Salivary glands carcinoma

Download high quality PDF file (466 kb)

Nasal cavity and paranasal sinuses carcinoma

Download high quality PDF file (630 kb)

External auditory canal

Download high quality PDF file (3450 kb)

Surgical peculiarities, SNB

Download high quality PDF file (44 kb)

Post-operative radiotherapy

Download high quality PDF file (548 kb)

Osteoradionecrosis

Download high quality PDF file (276 kb)

Target volume

Download high quality PDF file (1384 kb)

Organ preservation protocols

Download high quality PDF file (248 kb)

Chemoprevention

Download high quality PDF file (307 kb)

Anatomopathology

Download high quality PDF file (3591 kb)

Imaging of H & N tumors

Download high quality PDF file (4916 kb)

Clinical trials

Download high quality PDF file (680 kb)

Osteosarcoma

Download high quality PDF file (532 kb)

Nutritional support

Download high quality PDF file (324 kb)

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Contributors to the first edition


 

Imaging:

Emmanuel COCHE, M.D

Thierry DUPREZ, M.D.

Max LONNEUX, M.D.

Medical oncology

Jean-Pascal MACHIELS, M.D., Ph.D.

Oral & Maxillofacial surgery:

Hervé REYCHLER, M.D., D.M.D.

Sergio SICILIANO, M.D.

Otorhinolaryngology and Head & Neck surgery

Gautier DESUTER, M.D.

Marc HAMOIR, M.D.

Philippe ROMBAUX, M.D.

Pathology:

Birgit WEYNAND, M.D.

Radiation Oncology:

Vincent GREGOIRE, M.D., Ph.D.

Data Management:

Nathalie DELVAUX, R.N.

Independent reviewer:

Philippe MAINGON, M.D., Ph.D.

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Foreword to the fist edition (september 2001)


During a week in February 2001, the 12 members of the Head and Neck Tumor Board of the St-Luc University Hospital of the Université Catholique de Louvain, met in Combloux (Haute-Savoie, France) to review the available literature on the management of patients with head and neck malignancies, and build up diagnostic and therapeutic guidelines.

Nothing was left to improvisation! Each participant was assigned a given topic, within his own field of expertise - the whole spectrum of head and neck oncology was divided into 14 topics, from the lips to the larynx, including the nose, the skull base, the facial skin and the salivary glands-, and during the months preceding the meeting, they had to extensively review and summarize the pertinent literature in order to propose guidelines to the whole group. A rigorous methodology developed in "evidence-based medicine" was used. For every statement, a level of evidence (e.g. statement based on randomized studies or only on retrospective data collection) and a degree of recommendation (e.g. standard procedure versus experimental procedure) were added. A very strict time schedule was respected to allow each participant to present his review and to leave ample time for discussion with the whole group before unanimously accepting the amended guidelines. During 8 hours a day, all participants, driven by a critical spirit, enthusiastically discussed their peers' proposals and meticulously verified the pertinence of their statements. On difficult matters, we were fortunate to rely on the expert opinion of Prof. Philippe Maingeon from the "Centre anti-cancéreux" in Dijon (France) who kindly accepted our invitation to act as outside reviewer.

Beside the scientific work, three hours each day were devoted to alpine ski, hence demonstrating that the adage "mens sana in corpore sano" is of considerable importance in primary prevention! This outdoor activity greatly contributed to the excellent and friendly atmosphere of the group of eleven physicians and one clinical research associate.

Hereafter, you can appraise the result : 170 pages guidelines, harmoniously presented and based on an extensive review of the literature. These guidelines will be regularly reevaluated &endash;as they must be!- and modified when appropriate. This will an opportunity for future retreat ÷

As you will discover, the leitmotiv of our guidelines is " multidisciplinarity ". This it is not a empty word as we are strongly convinced that nowadays, patients with malignancies can only be correctly managed by dedicated physicians organized in a multidisciplinary tumor board.

We wish you an instructive reading and would very much appreciate to receiving any constructive comments regarding our work.

Brussels, September 2001.
 

Prof. V. Grégoire Prof. M. Hamoir Prof. H. Reychler

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Foreword to the second edition (september 2003)


Two year after the first edition of the Evidence-based guidelines for the management of patients with Head & Neck tumors, a second meeting was held to update the recommendations published in September 2001.

Few topics, i.e. management of the neck and postoperative irradiation, were modified in light of the new data. New topics, i.e. mandibular osteosarcoma, skin tumor of the head and neck area, nutritional support, were added. Last the presentation of the various protocols conducted within our Head and Neck Oncology Program were updated.

As for the first edition, we wish you an instructive reading of this second edition, and we would very much appreciate to receiving any constructive comments regarding our work.

Brussels, September 2003.

Prof. V. Grégoire Prof. M. Hamoir Prof. H. Reychler

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Pages: UCL School of Medecine | Radiation Oncology Dept. | Oral and Maxillofacial Surgery Dept.


Created by Dr . Pierre Mahy on August 28, 2001. Updated on May 21, 2006.